Nanobodies Target Proteins in the Brain that Cause Parkinson's Disease Symptoms
Although only done in animal models, researchers at Johns Hopkins are very hopeful about a new approach to addressing symptoms of Parkinson's Disease.
There is no cure for this disease that causes tremors, weakness, and even mood swings. It's also difficult to target specific proteins in the brain that cause these symptoms without impacting surrounding healthy proteins.
Proteins become misshapen and contribute to symptoms and scientists have been working on developing ways to untangle them. A new study done in rodent models shows using a nanobody can help untangle these problem proteins.
The nanobodies were able to target only the misshapen proteins, reducing build-up and preventing them from spreading to the cortex of the brain (where higher brain function occurs).
Researchers are hopeful this discovery will lead to future trials in humans to potentially slow down and reverse symptoms of Parkinson's Disease.
